Today i experienced 2 crash to desktops after hitting F5 to quicksave.
The first was in the morticians house after i opened his 2nd story door.
The second was in the cave underneath the graveyard after killing the scorcher goblin.
The first crash did not result in a corrupted save file and i was able to continue from where it crashed. I have not loaded the game yet to see if i can resume from my 2nd crash.
I'm getting a repeatable CTD trying to load a game I saved in the scorcher goblin cave. I saved this game normally.