I have similar/same problem.
Model: MacBook Pro (Retina, 15-inch, Early 2013)
OS: macOS Mojave Edition 10.14.2
RAM: 8 GB 1600 MHz DDR3
CPU: 2.4 GHz Intel Core i7
GPU:NVIDIA GeForce GT 650M 1024 MB
Intel HD Graphics 4000 1536 MB
The game will have a few seconds of black out and then return with a "Video System Warning," quoted "Nvidia graphics chips are not officially supported. Although you may not encounter any issues, we are unable to provide support for Nvidia related issues if you do."
After I pressed the OK button, the game sort of launch--still black out, and then crashed. Happens also to the D:OS (Classic), too, but not the D:OS(EE).
Here is the crash log
for launching D:OS 2.
Thanks! I would be happy to help out developers too.