When I first used the program I kept listing the wrong directory for "data" and it would crash immediately...Every time, no exceptions, as soon as I selected a tab after attempting to load. The correct data folder to use is of course the only data folder there is..;)...make sure that the path includes the data directory itself and not just the parent directory--or you'll crash as I did. Path name should read
X(your game install drive letter):/Divinity - Original Sin/Data
then you should be able to select a saved game and hit the load button and proceed from there without a problem. That's the only crash I've had with the MooseEdit program.
Also early on, I did notice that if I attempted to write back values the 1.0.107 game would not accept, then as soon as I booted the game and attempted to load the edited save the game itself would crash--not MooseEdit, the game itself would crash. Didn't know which crash precisely you might've been talking about.