Most of the books just give information (charm values, how to mix potions ect,funny stories)If by drugs you mean George's drudane plant, you can make a Super Drug potion with the alchemy skill that nets you 100 poison resistance and -100 spiritual resistance. If you bought a magic carpet from the scam artist in the pub, its basically worthless, but after you buy a few more worthless things from the guy he teachers you one level of trader's tongue skill.