When I open combat - or join combat - with a monk from stealth, the monk does not gain their bonus fist attack. This is a shame, that's exactly the sort of thing you want to do with a monk.
When Shadowheart engages in conversation near the Selune shrine at the Mill - I always get 'this option is no longer available', and there is no other option than to leave the conversation.
Withers will comment on Gale's bosom companion status - I can reply about 'just a night in the weave' - even though that scene had never occured, nor had i rejected it.
From there on, the game assumed I was romancing Gale [This was on honour mode, so I can't recreate it]
When freeing the Gnomes by killing all the guards and Warden, and then opening the cells, the Gnomes and Tiefs will run towards the spot where they jump - Then all stand still occupying the same 'square'. They cannot be interacted with, but leaving the area results in the death of the Gnomes/Tiefs. That is really, really sad.
[Left the area to try and reset their AI, because honour mode, can't reload - I also can't recreate, not taking that route again in my next run]
Also, on the Tief topic: I have never, ever seen Alfira among either the Tiefs in the prison, or the Illithid factory, amidst the battlefield corpses, nor in Baldur's Gate. Not sure why. Supposedly, you're supposed to get some reward or other when rescuing the Moonrise Tiefs, but I've never seen her past Act 1. This might not be a bug and just something I did wrong, but I can't imagine what that is.
I've had, in my last game 'Someone wants to talk to you' before resting, every time - even if there was no one that wanted to talk to me. Not even Scratch.