With cazador I was expecting sleet storm and sunlight to do more than it did. My Tav got initiative but Cazador was second and he used his boss power to take down my wizard. Gale (life cleric) used sunlight but Cazador just flew to the edge of the map ans started casting spells again. Jaheria was supposed to cast a second sunlight spell but she was paralyzed. Next time everyone had potions of guileful movement and I was fine.
I did metaknowledge House of Hope so who knows if I would have found it more difficult if I didn't know the boss powers.
Looking forward to more success stories but hard to beat "died by vampire bite"
Adding: On hording inspiration points. The sage background gives you inspiration from books so I carry inspiring books with me so I'm always at 4 before one of the moments. The book of dead gods, the secrets of shadow druids, the illithid book that Omelleum sells, druid diary and the final diary of the spider matriarch all give you inspiration points. If I'm lower than 4 before a difficult check I take a moment to read a book. Also means that Gale has points to spare.
I had no issues with Cazador. I definitely use daylight smack dab in the middle of the room. If the devs are going to go out of their way to show us the Astarion/Petras scene where he shoves Petras' face in the sunlight and it flakes off in ash, they're clearly showing us this is a vampire's weakness. Whether the player wants to use that weakness to their advantage is up to themselves.
I have the entire party on the bridge, then cut off the entry point with two walls of fire. The first wall of fire is for the bat swarms, and the second wall of fire is for the werewolves who try and jump the first. As Cazador is running towards my characters, I put one fire Elemental, one water Elemental and 1 radiant guardian surrounding him. If he so much as moves, they get an opportunity attack. You can also throw a Mind Sanctuary down. On tactician mode it originally makes bonus actions the same as actions; on Honour mode, it changed it to "Hasten creatures within it." I also use Danse Macabre as a "meat shield," in the unlikely event that any enemy makes their way past two walls of fire, the ghouls create another barrier. On Astarion's turn, I make him use ranged disarming attack and Cazador drops his weapon. Within 2-3 turns Cazador is already dead.
Oooo, also thank you for the Inspiration tip! I originally chose Artisan, for the bonus insight and persuasion, but I couldn't find that many places of inspiration. Selecting Sage would definitely help seeing as spellcasters/wizards are one of my favorite classes

At the very least, I can use that tip for Gale!

I was so sad I didn't even want to collect them afterwards, even considered deleting the run, so I just left
Aww D: That is sad

I thought you wanted to kill both sovereigns. In my run, I had Glut as a follower and the Duegars killed him. It was better he died this way. I didn't really want to kill him, and I wanted the Spaw rewards :3
Regarding sentimental attachment to NPCs, I put Raphael in my backpack on one of my runs. Originally he was the Stage 2 version, which was even cooler looking, but after a long rest he reverted to his devil version. I felt sad killing him, because when you go to the House of Hope, you can find his journal entries chronicling and following a bunch of adventurers

I was like AWWWW, Raphael likes us and I killed him for armor

*sigh* Sometimes I take him out and take pictures with him.
It turns out, if your throw him, he lands on his feet and poses. I'm not questioning it:
![[Linked Image from i.ibb.co]](https://i.ibb.co/6m8F6K1/Raphael1.png)
![[Linked Image from i.ibb.co]](https://i.ibb.co/gvMM4wm/Raphael2.png)