I didn't have any issues with two monitors after the patch - both 1680*1050, one 60Hz, the other 120Hz (NVidia drivers). The game worked as it always did.
Edit: There was one change: I've noticed that it now disables the "Aero" colour scheme of Vista and Windows 7 when the game is running - it didn't do that before. Larian says it's deliberate, and it certainly hasn't caused me any problems, it just seemed a bit unusual...
Last edited by Trippy; 08/12/10 01:50 PM.