I dont now, but I dont tink its possible.
You don't know? You work here

Thank you all for your responses. Mr.Loma, I started on assigning all the different keys to the controller last night via 3rd party software and at this point it really acts and feels just like it would on an xbox 360. The only places im running into trouble with that approach is getting target lock to function as it should and browsing inventory boxes.
Are there shortcuts when browsing the inventory of items in DNS (pc version)? Such how one could press the "B" button to close the item's inventory box and "X" to take all items on the xbox 360 version of D2:ED.
I hope so because that little tiny "x" is tedious to click on every box...even on a 60" tv, lol.