FPS drops sometimes out of the blue, from just walking around. Could be something loading outside the visible screen? (2 x GTX 680 in SLI, Quad Core etc). Runs flawlessly except for some random fps drops.
Dialogues need to be more intuitive. At this point very messy. Especially for a story line. When you talk to NPC when Journal is updated the link triggering the Journal update needs to be removed as a dialogue choice since its already in the Journal.
Too many NPCs have too many similar dialogue lines. Butter give them 1-2 lines but different from each other. Or just one line of misc dialogue. Or even better if NPC is just a villager and has no mission/quest make him say something in chat bubble instead of opening full dialogue window every time with every NPC.
(Alpha) Hopefully game will have more music tracks than in alpha

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(Alpha) Inventory badly needs a sorting option.
Money needs to count as players currency without taking whole inventory slot.
Potions need to have STAT/BONUS description in the tooltip. (Example: Minor Healing Potion: +50HP.)
Had 3 mushrooms and 2 empty flasks, for some reason I ended up with 2 poison flasks but 3 mushrooms were gone, not 2. 1sr potion took 1 mushroom, second potion took 2 mushrooms. Hmm, Something is amiss in potion crafting formulas.
Roderick joinparty script is messed up. No way to cancel out and party join interface is very unintuitive. Tried to chain him to existing party members (2) and wouldn't work. Couldn't cancel out either.
Map doesn't keep the open areas through save. If you load the game fog of war is reset again.
Dialogue with Orc Worrior outside the city West Gate loops on "What stone do you mean".
Screen doesn't scroll down, only does if mouse is on the either side of the ability bar. On the ability bar itself it won't scroll down(windowed mode). Game needs to have screen scroll also bound to arrow keys on the keyboard - its a standard biding for these types of games.
Double click on character portrait opens the Character window. It would be more intuitive if Right click would open character screen and double click on character portrait would center the screen on the character which portrait you clicked on. Right click does nothing right now.
During the dialogue camera needs to be locked and centered on the NPC you are speaking with.
Quest Journal needs to have "collapse/expand all" button. When you have many quests it gets messy. Would make sense it quests were at least sorted by Primary/Secondary/Side and were listed in their own sections/paragraphs.