It couldn't hurt to try different video modes.
Try deleting all of the files in the '
..\Divine Divinity\Run\Dynamic' folder.
This folder is used as a cache for the game. Files are created / copied there from the save game folder when you load, and written / copied from that folder when you save a game. The files will be re-created as required the next time you start Divinity. If there was a corrupt file in that folder, deleting the files should fix the problem.
Troubleshooting Tips (& manual install procedure)If you can't figue out the problem;
Wasteland-Enddungeons-screenie-spoiler 
