if you think about GPU overheating,
1. try the utility from your video card vendor and check GPU temperature (for my ASUS it's GPU Tweak 1/2). it would be enough to run any game in the background, as I could see in GPU Tweak
if it's really hot
2. try to remove the dust from its radiator.
maybe you have to disassembly entire cooling system and use new thermal compound on GPU chip.
I have GTX780 (w\o TI) also and I play 4k with ultra settings.
after using a vacuum cleaner GPU temperature decreases from 80C to 50-55C for my video card

and 80C is a cap from ASUS with its GPU Tweak utility and\or GPU BIOS settings.