I've had this bug several times now. During the first fight in Driftwood arena, about halfway through, my screen goes black except for the UI. I can still attack and move, but can't see what I'm doing. I actually managed to win the fight this way once, and after speaking to the Dwarf woman, teleported to the Driftwood Square waypoint, and everything was still black.
Playing the latest hotfix version through GOG Galaxy.
My specs:
Windows 10 Home 64-bit
Intel Core i5 4690K @ 3.50GHz
32.0GB Dual-Channel DDR3 @ 1066MHz
4096MB ATI AMD Radeon R9 380 Series (XFX Pine Group)