A Thunder rune in a power frame gives +3 Finesse and +15% Lightning damage to a weapon. I do believe Finesse is an attribute.
exactly ... I have already mentioned this:
And by using rune frames you can upgrade your damage runes to give attributes.
But it is still a damage rune (with added benefit). My point here was, that there is no difference in socketing your framed rune in your main or your offhand weapon.