Windows 10. AMD FX8350. R9 280X.
Initially I would like to note that there is huge performance difference between Vulcan and DirectX.
My specs are on the low end of minimum/recommended, so I did not complain on having to set everything to low on Vulcan, even though autoconfigure had it on Ultra.
Changing to DirectX, Ultra settings were working like a charm, similar to D:OS2, almost no performance issues (except some glitches, like emptying a buffer and having a half-a-second jump)
However, after three minutes or so, Windows crashed (blue screens still exist???) indicating the error code: Kernel_Security_Check_Failure.
Cheers