Apart from the performance problems which most have already said to experience (lobbed with the packaged in multiplayer de-sync), I haven't noticed many gameplay issues, other than these three things that heavily stood out to me.
1. Autopathing is very screwy, I have seen my character walk back and forth several times before going to the destination I had actually marked down.
2. I witnessed a bugbear corpse clip into the ground and start flailing like a Gmod ragdoll.
3. I knocked down the foundation block in the overgrown ruins with a ray of frost, watched it fall, watched it disappear. Nothing changed. The floor was still cracked and unchanged, but the block was gone.