Are you just getting near the chest or running your cursor over when you crash? They have fixed a bug moving the cursor over containers with magical items, which will be in the next patch, and have requested a save from someone getting a crash at a certain location, so will hopefully fix that as well. You could email them your save, or check if they want/need it.
If the next patch comes out before you finish act 2, you could go back for the amulet (there was some other good loot there as well, in my game, in addition to the quest reward you can get).