It is a few clicks every time you start the game, though, with a short delay as it starts each video. When I install a game, if there is no option to bypass the intro after watching it once, I will check if the videos are on the hard drive, and move them if so (to be deleted if the game goes straight to the main menu without complaining).

I found it a little annoying when Divinity did not save the 'always run' setting, and that is only a single keystroke per session to set.