The first appears easier to use; both are freeware (for personal use).
Hekko Virtual CDHekko Virtual CD creates a virtual CD-ROM drive on your Windows PC. This allows you to make images of your favorite CD-ROMs and use them without inserting a CD into a CD-ROM drive. Hekko Virtual CD: 1) improves the speed at which you access data, 2) stops you from having to switch disks in and out of your CD-ROM drive. Use Hekko Virtual CD to easily access your favorite games, favorite music or favorite software programs. Since Hekko Virtual CD uses HekkoScan(tm), nearly *any* CD can be imaged.
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Windows 2000/XP (Windows 98/Me not yet available)
Daemon ToolsDaemon-Tools is an advanced application for multiprotection emulation. It is further development of Generic Safedisc emulator and incorporates all its features. This program allows running Backup Copies of SafeDisc (C-Dilla), Securom, Laserlock, CDCOPS, StarForce and Protect CD (and many others) protected games. Also included is a Virtual DVDROM drive (Generic DVD-ROM) enabling you to use your CD images as if they were already burned to CD! DAEMON Tools works under Windows9x/ME/NT/2000/XP with all types of CD/DVDROM drives (IDE/SCSI) and supports nearly any CD protection.
BTW, for other software, try
this site (and its list of links).