Toss a teleporter stone into the throne room, and you can teleport past the guards. If you are a mage, you can use the swap places special move with one of the guards inside. Alternately, you can use an area effect spell that does not need a target (such as Poison Cloud) to kill them without a reputation drop (cast the spell near them, but not directly on them).
For your resistances, it looks like you drank a super drug potion. The effect wears off after a couple hours (I'm not sure the exact time).
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