Larian Studios Forums Divine Divinity (English) General reputation decreased because of orc

I did that once myself, testing a statuette I found. I re-loaded and returned to the same spot, but did not find any friendly orcs, and there were no green crosses on the mini-map
There is a very brief delay when switching back to human form, before alignments are adjusted. If you attack while transforming, the enemy can still be friendly, so your reputation drops.