She can be damaged by poison. This time when I played it as warrior, I used the following:
- set "drink restoration potion" to a hotkey
- set "drink shadow potion" to another hotkey
- drink shadow potion
- poison weapon
- go near Josephina
- release 2 scorpions
and now, when she is distracted by the scorpions,
- hit her with the poisoned sword.
- when she starts hitting on me, quickly drink restoration potions
- when she uses hell spikes, drink shadow potion and restoration potion.
- wait till she calms down or that disturb sight-thingie she always cast on me wears off
- start from beginning.