1)
Well there are people who live there so....
2)
AFAIK there is no one in that room, it's just an action that happens when you use the door.
3)
Yes
<span class='standouttext'>Spoiler : </span><span class='spoiler'>
If you hadn't molested the guards in the room before samuel you could have used it to lure 3 of the 4 to the gong
</span>
4)
<span class='standouttext'>Spoiler : </span><span class='spoiler'>
talk to Laurel who should be near those doors
</span>