SE => toss your pyramid over and enter.
center => this is the area of the alchemist - a very important place, once you have found out "cause of the plague" and get the new quest "find alchemist".
Missed => main quest as I explained above - let me guess: you have picked up a root and a strange fruit, looking like pumpkins? If so - drop them, find out the "cause of the plague" in Imp Village first.
