Windows is a very funny beast sometimes, especially when patches are involved.
Sometimes the best bet is to copy your saved games folder and its contents.
Totally uninstall the game.
Reinstall the game.
Reboot as required.
Install the latest patch and then put your copied saved games folder back.
I have found this has helped me with many games.
Good Luck <img src="/ubbthreads/images/graemlins/smile.gif" alt="" />