hiya raze.
i would agree with you that the particular quest is not the only contributor to the bug...but it's part of it. i could do ANYTHING else BUT talk to the sisters, and experience no problems what-so-ever.

the light i'm talking about is definitely part of the issue. no, i didn't go into sneak mode.
i tried this for over 2 full hours, with 8 different save spots and EVERY TIME i went to confront the sisters it created the issue.
like you, i have a zillion saves and can go back and test out theories quite easily.
i had a problem, so tried to fix it with patch 1.45.
that didn't work. and in fact caused the started game to say it had detected a problem, etc. etc. - so i went back to a place where it no longer gave me that fault and that was 3 days ago.
i slowly came forward (toward today) testing each save (and agreeing with the game's desire to 'fix' whatever it found) and found i had no issues with entering BF6 in act II - if i just went straight there.
not until i chose a later save (those after having talked with the sisters) did the problems surface.
so i went back again and completed tasks until i found the culprit.
i tested it at least 20 times, different ways.
the conversation with the sister sparks the bug. whether that is talking to a particular sister, having the one commit suicide or leaving their tent, i don't know. but something there is the problem.
i was quite thorough for the tools at hand.

but i also agree with you - there are a ton of reasons this could be the button for me, including past corruptions, etc.
that's for the larians to figure out.
and with the save file in their hands, hopefully they can.