Now that sharpen requires so much agility, are 2H-weapons useless?

I started a new game with my DK as an agility-based fighter using knifes. This seems to work very well - his weapon damage is based on agility, so he hits hard, and has high accuracy and evasion. His built-in armour means he doesn't need strength. Later on, I'll start boosting intelligence and make him a battlemage.

My hero is a ranged fighter, using crossbows ATM. When his strength and agility are high enough, I intend to switch to melee. I can't do that right away though because it requires both hgh strength AND high agility.

I have two other questions: are there any good 2H weapons that use agility for damage and have low strength requirement? And how does the stat-bonus damage work for spears and glaives?