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Do you have any other games or resource intensive applications, and do they cause any problems?
The rebooting may be a power supply problem if other programs do the same thing. Crashes and lockups can also be due to a heat problem, but I don't know about reboots.

Did you update your chipset drivers along with the rest of the driver updates?

If it is a memory leak, the topic Awful Slowdown contains some information on RAM programs and settings.
There are a couple memory testing programs you can try; Memtest86 and MS Windows Memory Diagnostic.



Well, I've spent much time updating drivers, chipsets, bioses etc etc...
and still the same problem. Memory tests turn out fine, and RAMidle doesn't seem to help. I can't find any error messages <img src="/ubbthreads/images/graemlins/disagree.gif" alt="" />
One thing to note is that the game ALWAYS crashes IMMEDIATELY after I attack a rat. I've killed the torturer guy, and the imp, and then the rats turn hostile. Game over.