Tiber are good exp. I always attack them right away at the start of act II. Imps, haven't attacked them yet but... hmm... I think I'll wipe out the whole town this time. <img src="/ubbthreads/images/graemlins/devil.gif" alt="" />
The frogs/rats/cats don't really annoy me that much. They can't hurt you. Only once did I get in a situation where they actually caused damage (and near death), I had like 4 frogs between me and a spell casting enemy and I couldn't get by, so I had to kill the frogs while I was hit by spells.