I've played thru act 2 twice. Once with a 1h slasher with everything +5/10 luck, and once with a wiz with like 10 luck total (from surv mostly). Didn't see much difference (actually my wiz got a few 3 slot items while my 1h slasher didn't get any higher then 2). It's probably like D2 magic find, you need a whole lot for it to do any good.