If you use the hotkey Crlt-F11 to take a screenshot, does one appear in the '..\Divine Divinity\Run\capture' folder?
If you highlight a potion, spell or weapon in the respective popup icon bars and hit Ctrl-F11 does an error message come up that that hotkey is already assigned to taking screenshots?
If you right click on an icon on your desktop and select properties, then assign it a Ctrl-Alt-Fx hotkey, can you use the hotkey to start the shortcut? Alternately, hitting F1 in most programs should bring up a help file. If not, there may be a problem with the function keys themselves.
Are you using a laptop or keyboard that reassigns the function keys by default, so you have to switch modes to actually use them as function keys?
