I have played BD under vista....
And i am playing it again now.... OK so i am cheating it profusely....
After numerous hours of studying, and crisis servers at work, the only thing that seems to unwind me (so i dont DREAM of work / studies) is to go monster slaying for a while.... So i run around the dungeons in near-god-mode and just bash a few moving targets to a pulp...
So far i havnt run into a single problem yet.... and i am running dual core(no cpu afinity is set , though i did alocate a seperate memory block for BD, since it makes one of my VPN programs go insane - so i just changed the memory block to a different block on both the programs - not sure if it was BD causing, or the VPN causing the issue they just always happened together). I have a 64 bit machine with vista and BD on, but i havnt played on that one yet, so my experience at the moment is solely based on 32 bit dual core.
I have a meeting with one of the Microsoft engineers on thursday for one of our servers.... .so i will at the same time ask him what can be the possible causes of this.