I started a new game, using only a single CPU. I didn't get out of the first area (with the cells) before I found my first corrupt item. It was a round shield that thought it was some boots. I found it in the rack in the cell with the mad man who thought we were demons and would eventually run out of the cell only to be killed...If anything, the single CPU made the corruption appear faster.
Sigh. Looks like I am going to have to play this on my laptop with XP.