We installed, updated and played Divine Divinity on a Vista machine (Vista Ultimate, the first official release) without any problems or any special action/change. Even without having to run it under compatibility mode.
If you still experience problems to run the game, please read the following:
- Did you try the compatibility mode options in Vista (right click the div.exe file and select Properties, then switch to the Compatibility tab)?
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Ensuring Application Compatibility in Vista (thanks to Raze for the link)
- Also make sure that you have enough priviliges/rights to install programs.
It could be that running the setup application seems to hang, but this is Vista "checking" the executable and that can take a while.