Isn't the movement system similar to Diablo? I would think if you were familiar with Diablo, moving in DD should be intuitive.
You can click and hold the mouse button down to direct your character where to move, rather than repeatedly clicking on the ground. The 'R' button toggle 'always run' mode, so the character will always run (with enough stamina), rather than walking or running depending on how far the mouse cursor is from the character.
With non-magical attacks, you just have to click an opponent once to start attacking.
You can hold the control key down to target the opponent nearest the mouse cursor. This doesn't cut down on the number of clicks required, but does help fighting groups of opponents.
