The best single character RPG is The Witcher, IMO. Hands down win, no rivals. That's the level all others must compete with...
Hard to refute, but I still think it could be improved upon, and has been in some aspects in previous games. On one hand, the biggest thing in my mind, is the "role" in RPG. The ability to choose from multiple character classes, with different abilities, is crucial. And can't forget male or female...less important to some, more to others. It's one of the things I loved about DD and Diablo. Gameplay strategies had to be adjusted for each type of character build. You can't have this in Witcher, at least not nearly to the same degree. On the other hand, you certainly have choices that affect the story and gameplay, and the story is pretty much phenomenal.