from this thread:
http://www.larian.com/forums/ubbthreads.php?ubb=showflat&Number=391132#Post391132

AMD Athlon 64 3700+ (single core)
AMD Dual-Core Opteron 2.4ghz
AMD Athlon 64 FX-57
AMD Athlon 64 3500+ (single core)

I have noticed around the web that people having the game not responding problem after the ladybug/ship cutscene seem to have older AMD processors.

I have tried everything in the related help threads to fix this on my sons AMD Athlon 64 3700+ system without any success.

Please list your processor if you are having the same problem and maybe we can get a fix/response from Larian.