AryzTheFenix;
In my experience the higher the resolution, the more likely it will cause a problem. On my system I could play at 1152x864 with very rare crashes opening the automap. At 1280x768 the crashes happened a bit more frequently, but I didn't play much as the text was starting to get a little small at that resolution. You will have to try it on your system to see if or how frequently you get a crash at a particular resolution.
I made sure to kill all the undead after Thelyron more for the experience points than the challenge. My first game I left the room to go after a couple stray skeletons, and had to reload after Zandalor showed up and robbed me of the extra experience/loot.
Shunmaha;
Sorry to hear reinstalling didn't help.