Would you be so kind as to zip your application data\divinity 2 folder and post it on the web?
I wonder if this is actually a fix, but I tried several work arounds already and might as well give it a shot.
A thing I noticed is that in some versions of the game, a registry key is made in hkey_local_machine\software\wow6432node for divinity.exe, some cases only in software\Larian studios and in some cases both.
As for using a crack to by pass securom, this does nothing for me.
English version with software\larian studios\divinity2 1 regkey (Language with value English) AMD Athlon 64 3400+ single core Nvidea Geforce 8500 GT 1,25 GB ram