I was having the CTD at the end of the third loading screen (credit screen). Happened regularly on the demo and DVD full game version. Tried all of the first aid suggestions, updated drivers, removed AV software, defragged my computer, etc... My system exceeds all of the minimum and most recommended requirements for this game.
Last night we dropped the resolution on my monitor and the game loaded for the first time. It then crashed during 'create new game' but at that point we were able to get into the main menu and lower the various video settings. Game runs now. Not sure if this will work for anyone else but just in case...
