Pick up everything you can. Even if it's not that valuable. If you have more stuff in your inventory than you can carry, drop the really cheap items. [ books you dont need, level 1 charms, some common ingredients and so forth ]
You should be able to sell some stuff before you get overloaded, but it did happen to me once.
If you get potions that you just dont use, sell those as well. No need to carry if u dont need.
Use the teleporters to break off from the quest and go back to town to unload.[ sell ]
If you are spending alot of money on potions you may want to invest skill into master herbalist so that you can make your own. [ and sell the ones u dont use ]
Figure out ways to SAVE money as well. Heal up naturally if the immediat threat has been killed. I know it takes a little time but if you are strapped for cash, it would be worth it.
Good luck