Though it doesn't affect any quests, I noticed that the two Orcs at the start of the Desert level are hostile when they should be friendly; Garth and Drox.

The Garth has a few lines of dialogue, but Drox also sells items. Here is a fix for when the Orcs are hostile and refuse to speak or sell items.

Fixing the Orcs, Garth and Drox :

Again, load of the hex editor.
Open the data.000 from your savegame folder.

Search for the text 'Orc drox186"
Ignore the first match and look for the second one which looks like this:
ASCII = "Orc drox186.....Orc drox"
HEX = "4F 72 63 20 64 72 6F 78 31 38 36 00 09 00 00 00 4F 72 63 20 64 72 6F 78"
Overwrite the hex value for the O's in both Orcs with 00 so the string now looks like:
ASCII = ".rc drox186......rc drox"
HEX = "00 72 63 20 64 72 6F 78 31 38 36 00 09 00 00 00 00 72 63 20 64 72 6F 78"

Now go back to the top of the document.

Start a search for 'Orc garth185"
Ignore the first match and look for the second one which looks like this:
ASCII = "Orc garth185.....Orc garth"
HEX = "4F 72 63 20 67 61 72 74 68 31 38 35 00 0A 00 00 00 4F 72 63 20 67 61 72 74 68"
Overwrite the hex value for the O's in both Orcs with 00 so the string now looks like:
ASCII = ".rc garth185......rc garth"
HEX = "00 72 63 20 67 61 72 74 68 31 38 35 00 0A 00 00 00 00 72 63 20 67 61 72 74 68"

Save the data.000 file
Run Divine Divinity, load the modified save and play!