I suppose it's nice that you can respec your skills, but it almost seems ill-advised to change your playstyle too much, given that you can't respec your attribute points. So if you invested much more in Strength than Dex/Int, it wouldn't help to respec from a warrior build to a ranger or mage build. But maybe it's better for simply fine-tuning your skills, perhaps not maxing something a second time around, or skipping things that are no longer useful (probably Healing late in the game?).