So you have not installed any programs since re-installing Windows? Some backup or media player software can install drive emulation programs, but if this is the first thing you've installed, that can't be the case here.
Some people have uninstalled emulation software, but had registry entries left behind which caused a problem with the copy protection. A clean re-install of Windows shouldn't have any traces of emulation programs, though.
Try contacting
Securom. They have a utility to remove / update / reinstall their drivers, and if you have more than one optical drive I've seen the lowest drive letter one recommended for use, with comments that Securom can be picky about that.
You could also try emailing supportintl@dtp-entertainment.com or support@larian.com, though Larian is on vacation for the next week.
