It depends on the game, but in general US and UK Xbox games are not compatible with the opposite console (NTSC vs PAL). Some people ordered the German PC version of D2:ED to play before the English release, but there was nothing mentioned in the forum about getting the UK Xbox version before the US release...
In any case, DKS should still be available in Canada, though (presumably in October), even without a North American publisher or date announced yet.
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