I'll answer as many of these as I can.
1.Couldn't tell you
2.The clues are special items in your Quest Item inventory,if you use them,you'll get a dialog telling you the clue
If you don't want to do that,i'll put the 5 answers in a box
1.White Snow - Mountain Rune
2.Fire God - Snake Rune
3.Moss Rat - Death Rune
4.Blue Moon - Shield Rune
5.Violet Blast - Gold Rune
3.When you use the anti-dust stuff,it spawns some blood trails leading from the bed to the wall.There is a button/switch on or near the wall(doing this from memory)
4.Not entirely sure what you're talking about here.If you are talking about the rune things around town,There is a statue of a dragon near the Prancing Seahorse that asks for the order of what the runes depict.Again,doing this off memory so I might be wrong here,but I believe the order was
1.Kitten
2.Totem
3.Totem
4.Maxos
5.Kitten
5.
You won't see her again until you get inside the vault