I'll answer as many of these as I can.

1.Couldn't tell you

2.The clues are special items in your Quest Item inventory,if you use them,you'll get a dialog telling you the clue
If you don't want to do that,i'll put the 5 answers in a box

1.White Snow - Mountain Rune
2.Fire God - Snake Rune
3.Moss Rat - Death Rune
4.Blue Moon - Shield Rune
5.Violet Blast - Gold Rune


3.When you use the anti-dust stuff,it spawns some blood trails leading from the bed to the wall.There is a button/switch on or near the wall(doing this from memory)

4.Not entirely sure what you're talking about here.If you are talking about the rune things around town,There is a statue of a dragon near the Prancing Seahorse that asks for the order of what the runes depict.Again,doing this off memory so I might be wrong here,but I believe the order was

1.Kitten
2.Totem
3.Totem
4.Maxos
5.Kitten


5.

You won't see her again until you get inside the vault