I would just like to give a follow-up.
I haven't played Divinity II since I created this post. So it's been SEVERAL months.
However, I decided to fire it back up, load up my save and see if the bug was somehow resolved. As we all know, drivers get updated from time to time, and the Nvidia PhysX driver has been updated a few times. Everything else on my system, except for Windows updates, has remained the same, including graphics drivers.
Anyways, I would imagine this bug I experienced may have been due to PhysX in some way. Either an NPC was out of place, or perhaps an item was colliding somewhere, or something. The bug is resolved, and I am back to playing again.