Well in the other post you seem to have discovered clue 5 as well, if chanelle just doesn't want to finish her perfume, its not vital to finishing the quest, either take clues 1 3 4 and 5 and guess where the orb for clue 2 goes, or search around the forums, cuz I know I've answered this and relinked the post a few times :P Hopefully she finishes making the perfume for you though so you can do madame eve's murder mystery.
(so yes, you do have to solve the murders for clue 2)