I've had problems running duel monitors since the patch as well. I think the problem happens more often when you are running two different monitors that are of different resolutions. I have my main that is 1920x1080 and my side one is 1024x768 but when I load the game it only detects the highest resolution of 1024x768, my side monitor. More then likely if i disabled the duel monitors it would work fine but its only done it since the recent patch and works fine with all my other programs. So hopefully they will release a new patch that will fix this problem and until then I will just have to hold out or play the game with little squatty people. =/