I'm also one of those players that likes to find it all and do it all in this game. I get particularly frustrated myself deciding whether or not to spend points on MR skill when there are so many choices for skills points to go (love it). I love this game

I'm on my 7th playthrough and just want to enjoy it to the fullest. I've spent a lot of time saving/reloading before MR or opening chests or turning in quests. It does get frustrating, but on the other hand, you have a lot more options and choices available to you and that's always a good thing!